Ionis Pharmaceuticals Inc

$ 74.48

-0.87%

05 Jun - close price

  • Market Cap 12,308,756,000 USD
  • Current Price $ 74.48
  • High / Low $ 75.96 / 73.81
  • Stock P/E N/A
  • Book Value 2.96
  • EPS -2.01
  • Next Earning Report 2026-07-29
  • Dividend Per Share N/A
  • Dividend Yield 0 %
  • Next Dividend Date -
  • ROA -0.07 %
  • ROE -0.68 %
  • 52 Week High 86.74
  • 52 Week Low 34.78

About

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapies in the United States. The company is headquartered in Carlsbad, California.

Analyst Target Price

$100.92

Quarterly Earnings

Mar 2026Dec 2025Sep 2025Jun 2025Mar 2025Dec 2024Sep 2024Jun 2024Mar 2024Dec 2023Sep 2023Jun 2023
Reported Date 2026-04-292026-02-252025-10-292025-07-302025-04-302025-02-192024-11-062024-08-012024-05-072024-02-212023-11-022023-08-09
Reported EPS -0.3-1.1481-0.610.85-0.93-0.4304-0.95-0.24-0.77-0.06-0.85-0.41
Estimated EPS -0.77-1.33-1.050.16-1.13-0.8444-1.16-0.76-0.83-0.83-0.89-0.7
Surprise 0.470.18190.440.690.20.4140.210.520.060.770.040.29
Surprise Percentage 61.039%13.6767%41.9048%431.25%17.6991%49.0289%18.1034%68.4211%7.2289%92.7711%4.4944%41.4286%

Next Quarterly Earnings

Jun 2026
Reported Date 2026-07-29
Fiscal Date Ending 2026-06-30
Estimated EPS -1.09
Currency USD

Previous Dividend Records

Jan 1970Jan 1970Jan 1970Jan 1970Jan 1970Jan 1970Jan 1970Jan 1970Jan 1970Jan 1970
Payment Date NoneNoneNoneNoneNoneNoneNoneNoneNoneNone
Amount $0.186$0.11$0.11$0.11$0.11$0.11$0.11$0.11$0.11$0.11

Next Dividend Records

Dividend per share (year): -
Dividend Yield -
Next Dividend Date -
Ex-Dividend Date -

Recent News: IONS

...
Price to book ratio of Ionis Pharmaceuticals, Inc. – XETR:ISI

2026-06-06 22:39:37

This article focuses on the price to book ratio of Ionis Pharmaceuticals, Inc. (XETR:ISI), providing a direct link to financial information for the company on TradingView. It highlights where to find specific financial data and market-related information for investors.

...
Ionis Pharmaceuticals Announces New Data on Olezarsen for sHTG Treatment

2026-06-04 16:09:09

Ionis Pharmaceuticals announced new data from its Phase III CORE and CORE2 studies on olezarsen, a drug designed to treat severe hypertriglyceridemia (sHTG). The drug demonstrated a 72.2% reduction in triglyceride levels and an 85% relative risk reduction for acute pancreatitis. Despite promising clinical results, GuruFocus indicates that Ionis Pharmaceuticals (IONS) is currently 38.1% overvalued, with a moderate GF Scoreâ„¢ of 69/100, and has seen significant insider selling.

...
Ionis to present new analyses from CORE and CORE2 pivotal studies supporting olezarsen for severe hypertriglyceridemia (sHTG) at upcoming congresses

2026-06-04 10:40:04

Ionis Pharmaceuticals, Inc. will present new data analyses from its Phase 3 CORE and CORE2 studies of olezarsen for severe hypertriglyceridemia (sHTG) at upcoming medical conferences. These presentations will detail how olezarsen impacts patients with different clinical backgrounds, building upon previous results showing significant reductions in fasting triglycerides and acute pancreatitis events. The U.S. FDA is currently reviewing olezarsen's marketing application for sHTG, with a target action date of June 30, 2026.

Ionis to present new analyses from CORE and CORE2 pivotal studies supporting olezarsen for severe hypertriglyceridemia (sHTG) at upcoming congresses

2026-06-04 10:39:23

Ionis Pharmaceuticals will present new data analyses from its Phase 3 CORE and CORE2 studies of olezarsen for severe hypertriglyceridemia (sHTG) at three upcoming medical conferences. These presentations will expand on previous results demonstrating olezarsen's significant reduction in fasting triglycerides and acute pancreatitis events with a favorable safety profile. The marketing application for olezarsen for sHTG is currently under Priority Review by the U.S. Food and Drug Administration, with a target action date of June 30, 2026.

Pancreatitis risk data on olezarsen ahead of June 30 FDA action date

2026-06-04 10:39:23

Ionis Pharmaceuticals (NASDAQ: IONS) announced it will present new data analyses from its Phase 3 CORE and CORE2 studies of olezarsen for severe hypertriglyceridemia (sHTG) at upcoming medical conferences. These presentations will provide further insight into how olezarsen impacts patients, with previous results showing significant reductions in fasting triglycerides and acute pancreatitis events. The marketing application for olezarsen is currently under Priority Review with the U.S. FDA, with a target action date of June 30, 2026.

...
Analyst Commentary Highlights Ionis Pharmaceuticals’ Upward Price Target and Valuation Amid Key Clinical Wins

2026-06-04 02:40:04

Ionis Pharmaceuticals' fair value has increased to $100.92 due to higher assumed revenue growth, improved profit margins, and a lower future P/E multiple, backed by positive analyst reports and new Buy initiations. While bullish analysts highlight the potential of Tryngloza and upcoming Phase 3 readouts as key drivers for significant sales opportunities, bearish views caution about valuation risks if product launches or clinical readouts fall short of expectations, pointing to the mixed views on future pipeline influence on current P/E multiples. The company faces both opportunities for substantial market share gains through expanding indications and strategic partnerships, as well as risks related to pricing pressures, regulatory hurdles, and reliance on late-stage assets.

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